Low-level laser irradiation inhibits abdominal aortic aneurysm progression in apolipoprotein E-deficient mice
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چکیده
منابع مشابه
Low-level laser irradiation inhibits abdominal aortic aneurysm progression in apolipoprotein E-deficient mice.
AIMS Increased early detection of abdominal aortic aneurysm (AAA) and the severe complications of its current treatment have emphasized the need for alternative therapeutic strategies that target pathogenetic mechanisms of progression and rupture. Recent in vitro studies from our laboratory have shown that low-level laser irradiation (LLLI) (780 nm) modifies cellular processes fundamental to an...
متن کاملInduced Aortic Abdominal Aneurysm in Apolipoprotein E– Deficient Mice
Baby Martin-McNulty, Doris M. Tham, Valdeci da Cunha, Jerrick J. Ho, Dennis W. Wilson, John Deficient Mice − Aneurysm in Apolipoprotein E Induced Aortic Abdominal − -Estradiol Attenuates Development of Angiotensin II β 17 Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2003 American Heart Association, Inc. All rights reserved. Avenue, Dallas, TX 75231 is published by the American Hear...
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BACKGROUND Abdominal aortic aneurysms (AAAs) in humans are associated with locally increased oxidative stress and activity of NADPH oxidase. We investigated the hypothesis that vitamin E, an antioxidant with documented efficacy in mice, can attenuate AAA formation during angiotensin II (Ang II) infusion in apolipoprotein E-deficient mice. METHODS AND RESULTS Six-month-old male apolipoprotein ...
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متن کاملA peptide antagonist of thrombospondin-1 promotes abdominal aortic aneurysm progression in the angiotensin II-infused apolipoprotein-E-deficient mouse.
OBJECTIVE Interaction of the activating sequence in thrombospondin-1 (TSP-1) with the conserved sequence (leucine-serine-lysine-leucine [LSKL]) in the latency-associated peptide region of latent transforming growth factor (TGF)-β complex is important in regulating TGF-β1 activity. We aimed to assess the effect of blocking peptide LSKL on the progression of pre-established abdominal aortic aneur...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2009
ISSN: 0008-6363
DOI: 10.1093/cvr/cvp149